HPLC Column, Zx Similars C8 Octyl, 3um, 4.0mm ID x 50mm Length, Cogent Brand. 1 EA. Special Order Item.

Additional Information:

Zx Similars C8™ Octyl is a traditional reversed-phase HPLC stationary phase manufactured on high-purity Type-B spherical silica with a fully endcapped octyl (C8) bonded phase. Designed as a cost-effective alternative to Agilent Zorbax® C8 columns, it offers comparable chromatographic behavior for USP L7 methods while providing the moderate hydrophobic retention, reproducibility, and reliability expected from a conventional C8 stationary phase. Compared to C18 columns, C8 phases generally provide reduced retention and faster elution of hydrophobic analytes.

65308-05P-4 is a 50 mm x 4.0 mm ID analytical column packed with 3 µm Zx Similars C8 particles. The short 50 mm length is optimized for rapid analyses, fast equilibration, and high-throughput workflows. The 3 µm particle size provides significantly higher efficiency and improved peak capacity than conventional 5 µm columns, while generating increased operating pressure that should be considered during method development. The 4.0 mm ID format is commonly selected for legacy methods and typically operates at approximately 0.8–1.5 mL/min.

This USP L7 column is ideal for hydrophobic and neutral compounds when less retention is desired than a comparable C18 phase. Common applications include pharmaceutical analysis, long-chain fatty acid separations, quality control testing, and fast analytical methods requiring chromatographic behavior similar to Agilent Zorbax® C8 columns. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.

Key Benefits

  • Type-B spherical silica stationary phase

  • Suitable alternative for USP L7 methods

  • Comparable selectivity to Agilent Zorbax® C8 columns

  • Fast analysis with 50 mm column length

  • Higher efficiency than comparable 5 µm columns

  • Lower retention than C18 columns

  • Excellent for hydrophobic and neutral compounds

  • End-capped C8 bonded phase

Typical Applications

  • USP L7 methods

  • Reversed-phase HPLC

  • Pharmaceutical analysis

  • Quality control testing

  • Method development

  • Long-chain fatty acid analysis

  • Fast analytical separations

  • Method transfer and validation

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: Zx Similars C8 Octyl

  • USP Classification: L7

  • Particle Size: 3 µm

  • Particle Type: Type-B Spherical Silica

  • Bonded Phase: C8 (Octyl)

  • Endcapped: Yes

  • Column Dimensions: 4.0 mm ID x 50 mm

  • Length: 50 mm

  • Recommended Flow Rate: 0.8–1.5 mL/min

  • Brand: Cogent

Special Order Item Information

This item is a Special Order Item manufactured specifically to customer requirements.

Important Notes

  • Designed for reversed-phase chromatography

  • Short column length provides rapid analyses

  • Higher efficiency than comparable 5 µm columns

  • Increased operating pressure compared to larger particle sizes

  • Compatible with HPLC systems capable of handling elevated backpressure

  • Provides less retention than comparable C18 stationary phases

  • Special Order Item


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